Researchers at Brown University and the Marine Biological Laboratory at Woods Hole, Mass., have found a physical connection between the herpes simplex virus and amyloid precursor protein, a protein ...

β-Secretase (BACE, Asp-2) is a transmembrane aspartic proteinase responsible for cleaving the amyloid precursor protein (APP) to generate the soluble ectodomain ...

Alzheimer's disease is likely caused by stalled protein processing in the brain, according to a new study. For several decades, researchers studying Alzheimer's disease have been working to understand ...

There are many unknowns around the causes of Alzheimer's, but one of the leading suspects is amyloid beta plaques. These form from amyloid peptides, and while some see these biomarkers as a chance to ...

Worldwide, 50 million people are living with Alzheimer's disease and other dementias. According to the Alzheimer's Association, every 65 seconds someone in the United States develops this disease, ...

The amyloid protein conformation, a structure that propagates as insoluble fibrils of aggregated β-strand-containing peptides, is a common feature of many neurodegenerative diseases. In Alzheimer, ...

Beta-amyloid plaques are considered a hallmark of Alzheimer’s disease, but they’re not the sole cause of the disease and its symptoms. Alzheimer’s is a complicated disease that experts are still ...

Watching the Alzheimer’s research world from the outside over the past two years has felt like a car ride over an unpaved mountain road without a seatbelt. In 2021, the US Food and Drug Administration ...

As the global population ages, Alzheimer’s Disease (AD) is a neurodegenerative disease which is becoming more common. A cure has not yet been found, but over a century of research has enabled ...