Clinical testing using various array comparative genomic hybridization platforms is being incorporated rapidly into cytogenetic testing algorithms. Comprehensive validation of these complex assays ...
Array-based comparative genomic hybridization is ushering in a new standard for analyzing the genome, overcoming the limits of resolution associated with conventional G-banded karyotyping. The first ...
infoQuant Ltd brings microarray technology closer to clinical use with its latest release of copy number analysis and interpretation software "oneClickCGH" and "CGH Fusion" for microarray-based ...
为探究儿童急性淋巴细胞白血病(ALL)的发病机制,研究人员对 67 例马来西亚正常核型的儿童 ALL 患者开展基于阵列比较基因组杂交(array-CGH)研究。结果发现了致病性拷贝数变异(CNVs)和意义不明变异(VUS),这有助于白血病分类和个性化治疗123。 儿童急性 ...
Due to its higher resolution, oligo array CGH has recently made strong inroads in the cytogenetic lab. It’s not surprising. With an increased sensitivity of more than 1,000-fold, microarrays can ...
Early efforts to examine genomic changes in the clinical setting relied on cytogenetic techniques such as chromosome karyotyping, a widely used approach to examine chromosomes and identify changes ...