Rather than completely blocking all downstream signals, the peptide developed in this study focuses on inhibiting the activation of p38-MAPK. This is enough to downregulate the development of mature ...

Melbourne researchers have made a world first breakthrough into creating blood stem cells that closely resemble those in the human body. And the discovery could soon lead to personalized treatments ...

Scientists have identified a protein that blocks the activity of bone-forming cells (osteoblasts) by stopping them from maturing during the journey to sites of bone formation, a new study has found.

Growth plates are areas of cartilage found at the ends of long bones. They play a role in the bone growth of children and teens. An injury to a growth plate can affect the development of a bone. While ...

Gain-of-function mutations in fibroblast growth factor receptor (FGFR) genes are known to cause a range of skeletal disorders, such as craniosynostosis and chondrodysplasia, which severely affect ...

Scientists have identified a protein that blocks the activity of bone-forming cells (osteoblasts) by stopping them from maturing during the journey to sites of bone formation, a new study has found.

Stem cells form the backbone of many cell-based therapies due to their unique properties, including the ability to self-renew and differentiate to many cell types. Multiple cell therapies deliver ...

NEW YORK - Scientists have discovered a mutant gene that triggers the body to form a second, renegade skeleton, solving the mystery of a rare disease called FOP that imprisons children in bone for ...