In a comprehensive research study, scientists have uncovered a previously unknown mechanism explaining how neurons survive botulinum neurotoxin type A (BoNT/A) exposure, despite the toxin's powerful ...

The use of toxin botulinum-A is one of the most rapidly growing areas in cosmetic dermatology. There is always news about this incredible substance. There are new indications, new techniques, and new ...

Several bacteria from the Clostridium genus produce botulinum neurotoxins—the most potent biological toxins known—that cause botulism by blocking neurotransmitter release from nerves. Typically, the ...

Local injections of botulinum toxin type A have been used to treat essential head tremor but have not been extensively studied in randomized trials. In a multicenter, double-blind, randomized trial, ...

BoNT/Aintoxication of LAN5 cells induces massive tRF changes. (A) Experimental design: 2×106 LAN5 cells/well were intoxicated by 10,000 MsLD50/mL BoNT/A, and small RNA-seq profiles from these cells ...

A hand wearing latex gloves hold a phial of clear liquid and a syringe. The medical professional uses the syringe to extract the medicine from the glass bottle. Conceptual with space for copy.

Researchers at Stockholm University have succeeded in creating a molecular blueprint of how one of the world's most dangerous toxins, botulinum toxin, is structured, stabilized, delivered and released ...