ERS Genomics Limited (‘ERS’), the CRISPR licensing company, and Dyadic Applied BioSolutions, a global biotechnology company producing precision-engineered, animal-free proteins and enzymes for diverse ...
本文报道了利用DNA-free CRISPR/Cas9技术对淀粉马铃薯品种"Kuras"中甾体糖生物碱(SGA)生物合成通路的关键基因进行定向编辑,成功获得SGA含量显著降低的突变体。研究靶向胆固醇合成前(SMO1-L、DWF1-L、DWF7-L)及合成后(16DOX、CYP88B1、TAMiso2)的6个关键基因,通过 ...
CRISPR-Cas9 is a promising approach for obesity therapy, targeting key genes involved in appetite regulation, metabolism, and fat storage. Preclinical studies showed strong metabolic benefits, ...
In the present study, we investigated whether electroporation could be used for one-step multiplex CRISPR/Cas9-based genome editing, targeting IL2RG and GHR in porcine embryos. First, we evaluated and ...
A research team has established a CRISPR/Cas9 gene-editing system for Chrysanthemum morifolium, targeting the CmPDS gene to explore gene functions and enhance breeding. By combining transient and ...
本文采用CRISPR/Cas9基因编辑技术构建喜盐菌(Halomonas campaniensis)XH26的hom/doeA基因缺失菌株,通过靶向代谢组学和RT-qPCR技术揭示 ...
Immunotherapeutic strategies have made huge strides in cancer treatment for many solid tumors over the past decade. But the promising results have failed to make a large change in the treatment of ...
In a first for adults in Singapore, scientists are conducting gene editing trials on heart patients to correct defects at their genetic source.
Data presented in a late-breaking presentation at the American Heart Association (AHA) Scientific Sessions 2025- -Phase 1 ...