The Collaborative Cross (CC) mouse resource has emerged as an indispensable platform for elucidating the genetic basis of complex traits. By combining high levels of genetic diversity from eight ...

Many human traits are influenced by multiple genes. Human genes can also carry slight variations in their gene sequences, which can have a wide range of effects. In some complex traits, those small ...

A new genetic mapping strategy reveals how entire networks of genes work together to cause disease, filling in the missing links left by traditional genetic studies. The technique could transform how ...

Scientists have developed a new method of genetic analysis, which extracts more precise data than previously used methods when looking at DNA, and will improve our understanding of the genetic basis ...

A new genome-wide mapping method finally shows how thousands of genes connect to drive disease. Biomedical researchers are working intensively to identify the genes that contribute to disease, with ...

Over the past decades, large-scale human genetic studies have identified numerous risk genes and variants associated with complex diseases and traits.

New research helps explain why disease-associated genetic variants can lead to variable clinical outcomes, influenced both by the patterns of secondary variants, or genetic background, and by how ...

Rare genetic traits are features that are uncommon within the general population. They can lead to different observable features or to rare physical abilities. Rare genetic traits are typically ...

An individual’s genetics and their environment both shape their personality. However, opinions differ on the degree to which each of these factors influences personality, and how they contribute to ...

What makes every person unique? Part of the answer is in our genes. A gene is a basic unit of heredity, the means by which traits get passed from one generation to the next, and genetics is the study ...