In 2005, two landmark papers describing novel cycle-array sequencing methods ushered in a new era in genetics. Known at the time as next-generation sequencing (NGS), these methods are now more ...

The field of gene expression continues to grow and evolve. Commonly used technologies such as microarrays are packing higher densities in a smaller footprint, and qPCR is becoming more accurate and ...

This study generated two million short DNA sequences, known as signature sequences or sequence tags, to identify and quantify both known and novel small RNA molecules. with the Breaking Science News ...

While DNA microarrays are already widely used, adapting the technology to RNA microarrays has proved difficult due to the lower stability of RNA. In 2018, the University of Vienna demonstrated how ...

A full-size, high-density RNA microchip is about the size of a fingernail and can contain up to 780 000 unique RNA sequences, each occupying a ~14 x 14 μm² area. The presence and the quality of the ...

Samples are commonly stored in a way that degrades RNA. Scientists are devising new ways to overcome this obstacle for RNA sequencing. RNA is more subject to degradation than DNA, whether chemical, ...

Hospital for Sick Children in Toronto researchers are reporting that targeted RNA sequencing can detect clinically actionable alterations in 87% of tumors and provide decisive findings where DNA-seq ...

In the early 1980s, David Gilmour, now an emeritus biochemistry and molecular biology professor at Pennsylvania State University, joined the laboratory of geneticist and biochemist John Lis as a ...

(Nanowerk News) An international research team led by the University of Vienna has succeeded in developing a new version of RNA building blocks with higher chemical reactivity and photosensitivity.