A study provides insights into the diversity of cancer-associated fibroblasts in white and black skin cancer and describes their different immunomodulatory roles in the tumor environment. The results ...

The use of immune-modulating fibroblasts, which are cultured under specific conditions to enhance their ability to suppress inflammation and address the root cause of cachexia and associated ...

Scientists have mapped underappreciated scaffolding cells in skin, known as fibroblasts. They show for the first time how fibroblasts go 'rogue' in many different diseases affecting multiple organs – ...

One promising strategy to remuscularize the injured heart is the direct cardiac reprogramming of heart fibroblast cells into cardiomyocytes. Researchers have identified TBX20 as the key missing ...

Cell-based therapies can be developed in various ways, but companies look for methods that are faster and more efficient. At Houston, TX-based FibroBiologics scientists turn fibroblasts into ...

The central nervous system (CNS) consists of several types of cells having varied specialized functions. While many of these cell types have been studied, fibroblast cells in the CNS remain ...

Cold Spring Harbor Laboratory postdoc Jeremy Nigri and colleagues in the Tuveson lab have discovered that the nervous system ...

NUDT21 regulates fibroblast senescence and is significantly decreased in aged and fibrotic lungs, impacting IPF progression. Alternative polyadenylation (APA) and NUDT21 downregulation enhance STAT3 ...

A new research paper was published on the cover of Aging, titled "Human senescent fibroblasts trigger progressive lung fibrosis in mice." Cell senescence has recently emerged as a potentially relevant ...