本研究针对抑郁症治疗药物副作用大、疗效有限等问题，通过慢性不可预知温和应激(CUMS)小鼠模型，发现6-姜烯酚(6-gingerol)能剂量依赖性地改善抑郁样行为，其机制是通过PPARγ通路调控小胶质细胞极化表型，抑制神经炎症。该研究为开发新型抗抑郁药物提供了 ...

本研究针对现有抗抑郁药物起效慢、副作用大等问题，通过CUMS抑郁模型结合PPARγ通路调控机制，首次系统阐明6-姜烯酚(6 ...

In the present study, we attempted to investigate the effect of [6]-gingerol on TPA-induced COX-2 expression in mouse skin in vivo and to explore underlying molecular mechanisms. Our study revealed ...

Do you suffer from bad breath? If so, a pungent compound found in ginger could be the answer to your problems. The substance, known as 6-gingerol, stimulates an enzyme in saliva that can break down ...

This is an ASCO Meeting Abstract from the 2014 ASCO Annual Meeting I. This abstract does not include a full text component.

The Kerala Agricultural University has been granted an Indian patent along with Arjuna Natural Private Ltd., Aluva, for developing a stable gingerol product from the ginger variety Karthika released ...

Capsaicin is a compound that provides many spicy foods with a kick. Some medical studies suggest that it might cause cancer. New research, limited at this stage to a mouse model, indicates that a ...

For many people, there's nothing more satisfying than a hot, spicy meal. But some research has suggested that capsaicin, the compound that gives chili peppers their kick, might cause cancer. Now ...

ATS 2013, PHILADELPHIA ─ Gourmands and foodies everywhere have long recognized ginger as a great way to add a little peppery zing to both sweet and savory dishes; now, a study from researchers at ...

Fresh ginger gets its characteristic bite from gingerol which is structurally similar to capsaicin, the molecule that gives chili peppers their heat. When dried, the gingerol is dehydrated to ...