Cytochrome P450 enzymes constitute a vast and diverse superfamily of haem‐containing proteins that orchestrate a broad array of oxidative reactions. Their inherent versatility enables them to catalyse ...
Light blue indicates the substrate-binding cavity inside the CYP enzyme. The CYP enzyme is unable to form a stable interaction with the atropisomer (aS)-CB45 because (aS)-CB45 collides (indicated by ...
In the broadest sense, immunomodulators are drugs that adjust immune responses, for example, modulation of cytokine levels. Cytokines are signaling proteins responsible for the regulation of immune ...