Since its landmark discovery in 1922, insulin has improved the health and extended the lives of more than 500 million people worldwide with diabetes mellitus. Yet the question of how this key hormone ...

CLEVELAND – August 4, 2014 – Since its landmark discovery in 1922, insulin has improved the health and extended the lives of more than 500 million people worldwide with diabetes mellitus. Yet the ...

Scientists have deciphered how the insulin molecule exploits a protective hinge to engage its primary binding site within the insulin receptor. "We discovered an essential mechanism for how insulin ...

Hyperglycemia and insulin resistance are common in critically ill patients, even if they have not previously had diabetes. Whether the normalization of blood glucose levels with insulin therapy ...