During the process of transcription, DNA is converted to RNA, a complex molecule that is able to carry genetic information outside of the cell's nucleus. This page guides you through the biochemical ...

Researchers confirm that the established pre-mRNA splicing mechanism that appears in textbooks cannot work in a subset of human short introns: A novel SAP30BP–RBM17 complex-dependent splicing has been ...

The interrupted non-coding regions in pre-mRNAs, termed “introns,” are excised by “splicing” to generate mature coding mRNAs that are translated into proteins. As human pre-mRNA introns vary in length ...

Pre-mRNA splicing in a subset of human short introns is governed by a distinct mechanism involving a new splicing factor, new research finds. The interrupted non-coding regions in pre-mRNAs, termed ...

Introns are perhaps one of our genome's biggest mysteries. They are DNA sequences that interrupt the sensible protein-coding information in your genes, and need to be 'spliced out.' Although you may ...

BLOOMINGTON, Ind. -- The sequences of nonsense DNA that interrupt genes could be far more important to the evolution of genomes than previously thought, according to a recent Science report by Indiana ...

Although you may not appreciate them, or have even heard of them, throughout your body, countless microscopic machines called spliceosomes are hard at work. As you sit and read, they are faithfully ...

The discovery of a single intron with aberrant splice boundaries in the primitive protozoan Giardia, raises questions about the origins of splicing. In September 19 Nature, Simpson and colleagues ...

Pre-mRNA splicing in a subset of human short introns is governed by a distinct mechanism involving a new splicing factor Protein-coding genes carry the blueprint for protein production. In higher ...

Our genome contains the genes that code for the proteins that carry out most biological functions, as well as a lot of other sequence. Some of that other sequence serves various regulatory roles, and ...

The origins of introns and their evolutionary role remain unclear. In the November 6 Proceedings of the National Academy of Science, Alexei Fedorov and colleagues describe the use of a computer ...