Updated platforms are needed to accurately model renal fibrosis, a debilitating cause of chronic kidney disease ...

A team developed a human iPS cell-derived kidney organoid-based proximal tubule-on-chip -- OPTECs-on-Chip -- that mimics in vivo renal physiology more closely than ever before. This model exhibits ...

Researchers developed tubuloids from adult kidney cells. When exposed to cisplatin, the model replicated key steps in the chronic kidney disease progression, including DNA damage, cellular senescence, ...

They used this model to understand the specific toxicity of a pre-clinical TCB tool compound that targets the well-characterized tumor antigen Wilms' Tumor 1 (WT-1) in certain tumors. Importantly, ...

aProximate TM is an advanced in vitro model of kidney proximal tubule cells (PTCs) that closely mimics physiological conditions. Derived from fresh human kidney tissue, aProximate TM PTCs are cultured ...

Chronic kidney disease (CKD) is a progressive condition that begins with tissue damage and gradually leads to loss of kidney function. The condition, which affects about 10% of the global population, ...

Chronic kidney disease (CKD) is a progressive condition that begins with tissue damage and gradually leads to loss of kidney function. The condition, which affects about 10% of the global population, ...

Please provide your email address to receive an email when new articles are posted on . Researchers found 54% of studies had risk for bias due to inadequate population selection. Moreover, 30% of ...