Although NR4A orphan nuclear receptors have been implicated in inflammatory gene expression and atherosclerosis, there is little information regarding their regulation by combinations of stimuli ...
DHA通过FFAR4介导cAMP-CREB-IκBα通路抑制鱼类炎症反应，体内实验显示FFAR4过表达减轻脂多糖诱导的炎症基因表达，而敲低加剧炎症；体外证实DHA协同FFAR4抑制炎症，其作用依赖DHA诱导钙离子动员和cAMP信号转导。 摘要 二十二碳六烯酸（DHA）通过游离脂肪酸受体4（FFAR4 ...
Cyclic adenosine 3,5-monophosphate (cAMP) is a cyclic nucleotide that serves as a vital second messenger in several signaling pathways. Credit: molekuul_be ...
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