Ordinary linear regression (OLR) assumes that response variables are continuous. Generalized Linear Models (GLMs) provide an extension to OLR since response variables can be continuous or discrete ...

Microbiome sequencing data are known to be biased; the measured taxa relative abundances can be systematically distorted from their true values at every step in the experimental/analysis workflow. If ...

Linear mixed models (LMMs) are a powerful and established tool for studying genotype–phenotype relationships. A limitation of the LMM is that the model assumes Gaussian distributed residuals, a ...