Irvine, Calif., Aug. 6, 2024 — Researchers led by the University of California, Irvine have discovered how the TREM2 R47H genetic mutation causes certain brain areas to develop abnormal protein clumps ...

Researchers led by the University of California, Irvine have discovered how the TREM2 R47H genetic mutation causes certain brain areas to develop abnormal protein clumps, called beta-amyloid plaques, ...

Exploring biology in its native environment is perhaps the ideal scenario for generating better hypotheses about the cellular interactions that influence—and drive—healthy and diseased states, ...

Perturb-FISH aims to address both challenges. Because this technique harnesses imaging spatial transcriptomics (iST), it offers high resolution and scalability, as ...