Pyramidal neurons have basal and apical dendrites, including an apical tuft. This preserved core structure suggests that they have conserved core functions, whereas structural variation in other areas ...

Scientists have uncovered how a newly discovered gene, NEK1, in which mutations have been linked to ALS cases, disrupts the function of the motor neuron and causes it to degenerate and die. The viral ...

A study has described how a gene mutation linked to amyotrophic lateral sclerosis (ALS) disrupts the stability of neurons and “chokes off” their nuclei, impairing their function. The research, ...

In Parkinson's disease and dementia with Lewy bodies, pathological aggregates of misfolded alpha-synuclein protein develop in brain neurons. Researchers have now described changes in hippocampal ...

"For nearly 100 years, scientists have been trying to name cells. They have been describing them in the same way that Darwin described animals and trees. Now the Blue Brain Project has developed a ...

A neuron model of Parkinson's disease and Lewy body dementias shows defects that could suggest treatments to halt or reverse cognitive impairments before the neurons die BIRMINGHAM, Ala. - A decay of ...

A decay of brain function is a hallmark of Parkinson's disease and dementia with Lewy bodies, or DLB. Specifically, cognitive dysfunction defines DLB, and nearly eight of every 10 Parkinson's patients ...

Is there a difference in brain structure between men and women? If we were to find such a difference in a single neuron, would it matter? One of the most useful models for studying these questions is ...