In the case of nucleic acid tests, polymerase chain reaction (PCR) has been the gold standard for single-molecule diagnosis. Single-molecule detection of pathogens, such as severe acute respiratory ...

Clustered regularly interspaced short palindromic repeats (CRISPR)–CRISPR-associated protein 13 (Cas13) has been rapidly developed for nucleic-acid-based diagnostics by using its characteristic ...

The early detection of lung cancer (LC) remains a critical challenge in oncology. This review explores the potential of exosomes (Exs) and cell-free nucleic acids (cfNAs) in the bloodstream as ...

(Nanowerk Spotlight) Advanced molecular diagnostics tests that can rapidly and precisely detect diseases within the home could revolutionize preventive medicine and improve global biosecurity. Nucleic ...

Back in the bad old days, dealing with DNA and RNA in a lab setting was often fraught with peril. Detection technologies were limited to radioisotopes and hideous chemicals like ethidium bromide, a ...

Please provide your email address to receive an email when new articles are posted on . The use of nucleic acid amplification testing for tuberculosis increased in the United States between 2011 and ...

Lateral flow assays (LFAs), such as the COVID-19 rapid test, are powerful devices to rapidly detect a protein’s presence or absence. This assay is so easy to perform that it enables at-home testing, ...

Protein detection sensitivity has historically lagged behind nucleic acid detection by 2-3 orders of magnitude due to the lack of intrinsic signal amplification. While digital methods such as Single ...

The rapid spread of animal diseases and pathogen evolution have long posed significant threats to the healthy development of animal husbandry. Traditional nucleic acid detection methods such as PCR ...

In a recent review published in the journal Trends in Analytical Chemistry, researchers provided a comprehensive overview of the current techniques used for severe acute respiratory syndrome ...