Researchers have revealed a new mechanism underlying how spatial distance between specific regions of DNA is linked to bursts of gene activity. Using advanced cell imaging techniques and computer ...
When the Nanog gene (green region) is inactive, one of the three enhancer regions is spatially far away. When active, the same enhancer region makes close contact, interacting with the other enhancers ...
New study by Chiba University, Japan in collaboration with Karolinska Institutet, Sweden, uncovers novel enhancer-promoter interactions that regulate gene expression during neuronal differentiation ...
Around 98.5% of human DNA is non-coding, meaning it doesn’t get copied to make proteins. A new study has connected many of these non-coding regions to the genes they affect and laid out guidelines for ...
Researchers at Kyushu University have revealed how spatial distance between specific regions of DNA is linked to bursts of gene activity. Using advanced cell imaging techniques and computer modeling, ...
Neuropsychiatric disorders are becoming increasingly prevalent. Given their complex and multifactorial pathogenesis, there is an urgent need for effective and targeted therapies that can improve ...