Background: Granulomas were frequently misdiagnosed as peripheral lung cancers (PLCs) due to their similarities in imaging findings. This study aimed to establish a classification system based on thin ...

One of the main challenges for tuberculosis (TB) therapy is how to deliver drugs to the site of disease. Once the body’s immune system is infected with tuberculosis, it forms granulomas—tight clusters ...

Pulmonary sarcoidosis is a condition that causes tiny groups of immune cells to clump in your lungs. These groups of cells form swollen, inflamed lumps called granulomas. Granulomas can make it hard ...

Chest CT-based radiomic analysis revealed 16 distinct features that could differentiate tumourlets (TLs) from granulomas, with flatness showing a specificity of 100% and long-run high grey-level ...

Researchers have found that approved drugs that were originally shown to normalize blood vessels surrounding tumors (to improve drug delivery to cancer cells) can enhance the delivery of ...

BOSTON – Tuberculosis (TB) is often overlooked in developed countries such as the United States, but this bacterial infection remains one of the deadliest diseases globally and results in millions of ...

Neutrophils induce anti-inflammatory -- or M2 -- macrophages deep in their granulocyte core. The dense globular structures of granulomas in animals, particularly in the lungs, have been studied.

The immune response against tuberculosis (TB) infections develops at least twice as slowly as that triggered by other infectious diseases that affect the lungs. A study in non-human primates by ...

See References Table 1 in the Supplementary Appendix, available with the full text of this article at NEJM.org, for additional references pertaining to this table. An adverse prognosis indicates a ...

In this Journal feature, information about a real patient is presented in stages (boldface type) to an expert clinician, who responds to the information by sharing relevant background and reasoning ...