In clinical trials with sequential patient entry, fixed sample size designs are unjustified on ethical grounds and sequential designs are often impracticable. One solution is a group sequential design ...

Stay up to date on the latest science with Brush Up Summaries. What Is Single Cell Sequencing? Single cell sequencing is a collection of methods that researchers use to isolate and analyze sequence ...

PLAMseq utilizes a rapid biotinylation enzyme called TurboID, which tags nearby proteins, enabling the genomic loci and ...

This research, led by Prof. Haichen Wu from the Institute of Chemistry, Chinese Academy of Sciences (CAS), and Prof. Lei Liu from the Institute of High Energy Physics, CAS, alongside their ...

Genetic variants that cause rare disorders may remain elusive even after expansive testing, such as exome sequencing. The diagnostic yield of genome sequencing, particularly after a negative ...

This image illustrates the typical steps in next-generation sequencing (excluding single-molecule sequencing methods). The process begins with isolating genomic DNA (a) and breaking it into short ...

Many life-saving drugs directly interact with DNA to treat diseases such as cancer, but scientists have struggled to detect how and why they work -- until now. Many life-saving drugs directly interact ...

Cambridge, MA - Traditional bisulfite sequencing damages DNA, while enzyme-based alternatives are inconsistent. A novel methylation analysis method, called UMBS-seq, was published this week in Nature ...

According to Jonathan M. Rothberg, Ph.D., CEO, founder, and chairman of Ion Torrent, his company’s semiconductor sequencing technology represents a quantum advancement in DNA sequencing. Ion Torrent™ ...

Global Nanopore Sequencing Market OverviewThe nanopore sequencing market is projected to grow at a CAGR of around 11% during the forecast period, driven by rising demand for real-time, portable DNA ...