Tumor-wide RNA splicing aberrations and their potential as therapeutic neoantigen targets. Phase 1/2, open-label, first-in-human study of the anti-GPC3 T-cell engager SAR444200 in patients with ...

Out of touch: Understanding the frequency and trajectory of chemotherapy-induced neuropathy peripheral (CIPN) in breast cancer survivors. Incidence of ocular toxicities in patients with ...

Breast cancer remains one of the most prevalent and life-threatening forms of cancer, impacting millions worldwide. This malignancy's heterogeneity and complexity have long posed significant ...

A comprehensive review article titled “Bioinformatics perspectives on transcriptomics: A comprehensive review of bulk and single-cell RNA sequencing analyses,” published in Quantitative Biology, ...

Scientists developed a new mRNA platform that keeps vaccines and therapies effective in older adults and patients with obesity, where current treatments often lose potency. (Nanowerk News) Researchers ...

Single-cell RNA-seq (scRNA-seq) has spent the past decade maturing into a foundational technology. Over that time, the technology has both laid the foundation for building cell atlases and allowed ...

Researchers uncover how distinct cell populations and fibrotic signals drive permanent scarring after rotator cuff ...

Essentially all cells in an organism's body have the same genetic blueprint, or genome, but the set of genes that are actively expressed at any given time in a cell determines what type of cell it ...

For people living with human immunodeficiency virus (HIV), life-saving antiretroviral therapy keeps their HIV-infected immune cells from making new copies of the virus, preventing illness and ...

Scientists at Gladstone Institutes, in collaboration with a team at the San Francisco Veterans Affairs Medical Center, have developed a novel tool—named HIV-seq—for profiling the features of rare ...