Background A resemblance of pancreatic tumours to their native tissue architecture remains largely unexplored, while it may ...

一篇发表在2025年《Nature Genetics》上的重磅论文，题目为“Single-cell and spatial transcriptomics reveal mechanisms of radioresistance and immune ...

A novel spatial transcriptomics atlas developed by Northwestern Medicine scientists may improve the understanding of niche cellular interactions in the gastrointestinal tract that promote the ...

引言如果一个基因被敲掉后，肿瘤更容易转移，我们通常会问：这个基因调控了什么通路？但随之也出现了一个更难、也更接近真实生命过程的问题：这个基因是在组织里的哪个位置发挥作用？5月26日，《Cell》的研究报道“Uncovering spatially ...

Biological systems are inherently three-dimensional—tissues form intricate layers, networks, and architectures where cells interact in ways that extend far beyond a flat plane. To capture the true ...

Applying single-cell RNA sequencing has led researchers to be able to profile the entire transcriptome of cells. However, these transcriptomes prove difficult to link back to their original location ...

Knowing the location of a gene within intact tissue or a single cell allows scientists to unlock unknown cellular functions. This information is often lost in most genetic sequencing techniques, but ...

Researchers reveal the intricate molecular landscape of triple-negative breast cancer (TNBC), uncovering actionable spatial archetypes and gene signatures that pave the way for personalized therapies ...

Key opportunities in the Global Spatial Genomics and Transcriptomics Market include technological advancements in spatial analysis, increased research funding, and integration of AI for data ...