2026年4月17日，北京大学基础医学院邓宏魁院士课题组在Cell上发表了题为“p53 safeguards chemical reprogramming of human somatic cells toward pluripotency”的研究论文（图1）。 图1. 该研究相关论文首页截图 该研究发现，关键肿瘤抑制因子p53在化学重编程中发挥核心保护作用，打破了“p53阻碍细胞重编程”的传统认 ...

Endogenous Retroviruses (ERVs), relics from ancient viral infections, form a significant part of vertebrate genomes, including humans, where they constitute ...

A single-atom nanozyme mimicking cytochrome c oxidase restores mitochondrial energy production in stem cells, shifting their ...

A team led by researchers has discovered that a group of cells located in the skin and other areas of the body, called neural crest stem cells, are the source of reprogrammed neurons found by other ...

A mature cell of one type can be turned into a mature cell of another type without the cell having to pass through an earlier stage of development. This is called direct reprogramming, a reliable but ...

A team led by researchers at the University of Toronto has discovered that a group of cells located in the skin and other areas of the body, called neural crest stem cells, are the source of ...

Researchers at Oregon Health & Science University have uncovered a key reason why immunotherapy has largely failed in ...

Pair showed that adult cells can be reprogrammed to an embryonic state. I think that all Nobel prize winners should sport badass hair like this Gurdon guy. On a more serious note, this is an awesome ...