It appears that there may be a compatibility issue between some iterations of Apple mice and certain portable models. MacFixIt reader J. Strauss writes "I have an iBook 12" dual USB, and a Titanium ...

Rosemary Brown describes a problem noted by a few other MacFixIt readers, where a UPS (uninterruptable power supply) seems to "hog" the chain, and produce strange problems for the keyboard and mouse. ...

Fix USB Root Hub via the Power Management settings. Update or reinstall the USB Hub driver. Reset the system BIOS to default. 1] Fix USB Root Hub via the Power Management settings The Power Management ...