THE procedures for the estimation of enzymes of the urea cycle reported by Brown and Cohen 1 have made it possible to study quantitatively the effect of hormones on the individual reactions of the ...

Urea cycle disorders (UCDs) constitute a group of rare, inherited metabolic conditions arising from deficiencies in key enzymes of the urea cycle – the biochemical pathway responsible for converting ...

This release is available in German. The urea cycle is a metabolic pathway used in mammals to incorporate excess nitrogen into urea and remove it from the body. However, it appears to play a far more ...

Urea cycle disorders (UCD) are a group of rare disorders that are categorized as inborn errors of metabolism. These disorders have serious implications, often resulting in irreversible neurological ...

Researchers have revealed the presence of a functional urea cycle in the star-shaped cells of the Alzheimer's Disease (AD) brain. Key results point to the role of the urea cycle in amyloid-beta plaque ...

An Indiana University School of Medicine physician scientist is making strides in understanding the molecular origins of fatty liver disease, a leading cause of liver failure in the United States. By ...

Lysinuric protein intolerance (LPI) is an autosomal recessive disorder caused by variants in the SLC7A7 gene, leading to impaired transport of dibasic amino acids across intestinal and renal membranes ...

A physician scientist is making strides in understanding the molecular origins of fatty liver disease, a leading cause of liver failure in the United States. An Indiana University School of Medicine ...