This study reports an important and novel finding that TENT5A, an enzyme involved in fine-tuning poly(A) tail length on selected mRNAs, is required for proper enamel mineralization in mice. The ...
Real-World Plasma Thymidine Kinase Activity in High-Risk and Metastatic Hormone Receptor–Positive, Human Epidermal Growth Factor Receptor 2–Negative Breast Cancer Treated With Cyclin-Dependent Kinase ...
Recent trends in cancer distribution and survival outcomes among adolescent and young adult patients: A national data analysis.
LNP–mRNA drug products are produced by mixing the nucleic acid drug substance with various lipid components, such as phospholipids, cholesterol, PEG–lipids and ionizable lipids, resulting in a ...
Researchers at Harvard Medical School and Brigham and Women's Hospital designed an ingestible capsule that delivers liquid mRNA to the intestines, producing gene expression and reducing inflammation ...
A research team has developed a biodegradable polymer-based delivery system that efficiently transports mRNA. A research team led by Professor Won Jong Kim from the Department of Chemistry at POSTECH, ...
Propagation of expression noise from mRNA to protein level is influenced by variation in availability of ribosomal machinery.
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