The New York Giants play host to the San Francisco 49ers on Sunday in a battle of teams missing multiple star players on both sides of the ball.

Watch the San Francisco 49ers top plays vs. the New York Giants from Week 9 of the 2025 NFL season. San Francisco 49ers RB Christian McCaffrey recorded his third touchdown of the game, surpassing Marshall Faulk for the most games with both rushing and receiving TDs in 49ers history.

The San Francisco 49ers defeated the New York Giants on Sunday at MetLife Stadium. How did it affect their standing heading into Week 10?

The last of these postseason games came back in 2011 in the NFC Championship game, when the Giants defeated the 49ers on the road, 20-17, to cap off their improbable run to Super Bowl XLVI, where they went on to beat the New England Patriots on that stage for the second time in four years.

San Francisco 49ers running back Brian Robinson Jr. found the end zone for the first time this year on Sunday, and his teammates were thrilled.

Since the injury avalanche hit the 49ers have managed to keep their heads above water and not suffer any bad losses. After losing in Week 8 to the Houston Texans on the road, the spotlight gets a little brighter for a group that has been pushed into bigger roles with a handful of injuries for San Francisco on both sides of the ball.

San Francisco 49ers QB Mac Jones got effective protection to beat the Giants, but credit some of that success to Kyle Shanahan's plan for how to keep New York's vaunted pass rush from being a factor.

The San Francisco 49ers' fears about the injury to rookie defensive end Mykel Williams were confirmed Monday afternoon when a source told ESPN's Jeremy Fowler that Williams tore the anterior cruciate ligament in his right knee.