Loss of the glutamate transporters EAAT5b and EAAT7 disrupts wavelength-specific visual processing and UV-dependent prey detection in zebrafish, revealing their key roles in modulating light ...

This study provides fundamental information on how Arg-II participates in cardiac aging. The phenotypic data provide convincing evidence of non-cell-autonomous contributions to aging-related ...

The first biologically inspired computer model, comprising multiple multisensory correlation detectors, can integrate spatially and temporally congruent audiovisual information in a similar way to ...

The pathogenic bacteria Shigella avoids detection inside hosts cells by degrading RNF213, the protein responsible for sensing the presence of intracellular pathogens.

Sub-membrane microtubule array, known to prevent excessive glucose-stimulated insulin secretion, depends on kinesin-1 KIF5B, which moves microtubules to both generate and remodel this array, ...

The role of megafaunal exploitation in early human evolution remains debated. Occasional use of large carcasses by early hominins has been considered by some as opportunistic, possibly a fallback ...

This paper describes Unbend - a new method for measuring and correcting motions in cryo-EM images, with a particular emphasis on more challenging in situ samples such as lamella and whole cells. The ...

This revised manuscript presents an important characterization of mouse auditory cortex receptive field organization, utilizing two-photon imaging of specific subpopulations. They demonstrate a ...

This study presents a valuable finding on mutations in ZNF217, ZNF703, and ZNF750 through 23 breast cancer samples alongside matched normal tissues in Kenyan breast cancer patients. The evidence ...

The manuscript concerns a fundamental and controversial question in Trypanosoma brucei biology and the parasite life cycle, providing further evidence that slender bloodstream forms can indeed infect ...

Muscle-derived branched-chain amino acids support thermogenesis in brown adipose tissue, thereby helping maintain body temperature during impaired muscle function or physiological stress.

This study presents valuable findings on the role of KLF6 in in vitro endothelial cells exposed to altered (high or low) shear stress with a customized microfluidic device to investigate mechanisms of ...