Background: Cardiovascular disease (CVD) causes more than 50% of deaths in patients with advanced chronic kidney disease (CKD). Clinical studies suggest that kidney-derived factors contribute to CVD ...

Background: Patients with prior ischemic stroke are at high risk for recurrent stroke and other major adverse cardiovascular events (MACE). The benefits of achieving very low levels of low-density ...

CoV-2, has led to the first approval of mRNA vaccines in humans. By producing the full-length SARS-CoV-2 Spike protein, they ...

Cardiovascular and metabolic health are influenced by the circadian system, which regulates 24-hour rhythms across numerous physiologic processes. Disruptions to circadian rhythmicity can adversely ...

An official, Open Access journal of the American Heart Association and the Society of Vascular and Interventional Neurology ...

BACKGROUND: A 3-dimensional hyperboloid model has been proposed to characterize ventricular tachycardia (VT) circuitry. We ...

Circulation: Cardiovascular Quality and Outcomes A catalyst for outstanding clinical and epidemiological science and policy information that enhances cardiovascular health and healthcare ...

A recent study by Shukla and colleagues, published in the Arteriosclerosis, Thrombosis, and Vascular Biology Journal, advanced our understanding of different aortic smooth muscle cells in disease-free ...

Platypnea-orthodeoxia is a relatively uncommon but striking clinical syndrome characterized by dyspnea and deoxygenation accompanying a change to a sitting or standing from a recumbent position. Since ...

The effects of both direct and reflexly induced increases in sympathetic activity on the blood flow to an extremity at rest and during muscular activity have been studied. When the O2 uptake of an ...

Background: Little correlation exists between the burden of ischemia and severity of angina in patients with stable coronary artery disease. This placebo-controlled, n-of-1 study investigated the ...

We prospectively investigated the associations of serum total and HDL cholesterol and total/HDL cholesterol ratio with total and type-specific stroke incidence among 58 235 Finnish people aged 25 to ...