High-concentration injectable formulations present unique challenges. Poor solubility issues are often associated with small-molecule APIs formulated for oral administration. Solubility is also ...
If you remember back to the Ye Olde times of your probationary period, you might remember the hazardous materials-operations level training segment. In that class, instructors said a whole bunch of ...
Modern methods and modeling offer a better way to understand solubility issues and solve today’s complex formulation challenges. Poor solubility is an ongoing challenge in pharmaceutical development.