Immune low-response states significantly impact the effectiveness of immunotherapy in cancer treatment. These states ...

Initially, cells are dissociated from liver tissues into single-cell suspensions using in vivo enzymatic perfusion or ex vivo digestion methods. The cells of interest are then enriched from the ...

A comprehensive review article titled “Bioinformatics perspectives on transcriptomics: A comprehensive review of bulk and single-cell RNA sequencing analyses,” published in Quantitative Biology, ...

Scaling up single-cell sequencing studies allows scientists to uncover rare cell types, better understand disease states, and track cellular changes over time. However, processing, assaying, and ...

This article explores how single-cell multiomics and spatial transcriptomics are illuminating early pregnancy, uncovering ...

Scientists at Duke-NUS Medical School have developed two powerful computational tools that could transform how researchers ...

The field of immunogerontology investigates age-associated declines in immune function, particularly focusing on the reduced lymphoid potential of ...

Kimchi may do far more than add flavor to meals—it could help fine-tune the human immune system. A clinical study using advanced single-cell genetic analysis found that regular kimchi consumption ...

Scientists have discovered, for the first time, how root cells respond to their complex soil environment, revealing that roots actively "sense" their microenvironment and mount precise, cell-specific ...