ebm.bmj

Reconsidering the role of tramadol in chronic pain management

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Correspondence on 'Less is more for patients, practitioners, public and planet: a taxonomy for the harms of too much medicine

Gram et al ’s taxonomy of the harms of ‘too much medicine’ offers a valuable and timely framework for understanding how medical excess affects patients, practitioners, the public and the planet.1 ...
ebm.bmj

How methodological pitfalls have created widespread misunderstanding about long COVID

The existing epidemiological research on long COVID has suffered from overly broad case definitions and a striking absence of control groups, which have led to distortion of risk. The unintended ...
ebm.bmj

Alcohol and atrial fibrillation: to or not to drink?

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Early experience with the FDA’s regulatory review of novel gene therapies

Correspondence to Dr Jeremy Puthumana, Yale University School of Medicine, New Haven, Connecticut, USA; jeremy.puthumana{at}yale.edu Contributors JP and JR drafted the manuscript. JP and ACE acquired ...
ebm.bmj

Estimates of the minimal important difference to evaluate the clinical significance of antidepressants in the acute treatment of moderate-to-severe depression

The efficacy of antidepressants in the acute treatment of moderate-to-severe depression remains a controversial issue. The minimal important difference (MID) is relevant to judge the clinical ...
ebm.bmj

Superiority trials: raising the bar of null hypothesis statistical testing

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077 How can shared decision-making turn into paternalism – and how should we think about this ethically?

Introduction When a health professional overrides a patient’s preferences for the patient’s own good, we have a case of paternalism. Paternalism is commonly considered ethically problematic and ...
ebm.bmj

43 Clinician and health service interventions to reduce the carbon footprint of health care: a systematic review

Background The global health sector is responsible for approximately 5% of global net carbon emissions and is therefore a major contributor to climate change. Reducing unnecessary tests and treatments ...
BMJ Evidence-Based Medicine

Comparing traditional and AI-enhanced strategies for developing patient decision aids: a multiple case study

Objectives Our objective was to develop and test prompts designed to generate balanced, evidence-based information from ...
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Effects of various exercise interventions in insomnia patients: a systematic review and network meta-analysis

Objectives To compare the effectiveness of different exercise interventions in improving sleep quality and alleviating insomnia severity among patients with insomnia. Design Our study design was a ...
ebm.bmj

Rapid reviews methods series: Guidance on literature search

This paper is part of a series of methodological guidance from the Cochrane Rapid Reviews Methods Group. Rapid reviews (RR) use modified systematic review methods to accelerate the review process ...