Background: Patients with prior ischemic stroke are at high risk for recurrent stroke and other major adverse cardiovascular events (MACE). The benefits of achieving very low levels of low-density ...

Background: Cardiovascular disease (CVD) causes more than 50% of deaths in patients with advanced chronic kidney disease (CKD). Clinical studies suggest that kidney-derived factors contribute to CVD ...

CoV-2, has led to the first approval of mRNA vaccines in humans. By producing the full-length SARS-CoV-2 Spike protein, they ...

BACKGROUND: A 3-dimensional hyperboloid model has been proposed to characterize ventricular tachycardia (VT) circuitry. We ...

Cardiovascular and metabolic health are influenced by the circadian system, which regulates 24-hour rhythms across numerous physiologic processes. Disruptions to circadian rhythmicity can adversely ...

Background: Little correlation exists between the burden of ischemia and severity of angina in patients with stable coronary artery disease. This placebo-controlled, n-of-1 study investigated the ...

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Platypnea-orthodeoxia is a relatively uncommon but striking clinical syndrome characterized by dyspnea and deoxygenation accompanying a change to a sitting or standing from a recumbent position. Since ...

We have recently shown that the extracellular matrix molecule agrin promotes heart regeneration after myocardial infarction in nonregenerating mouse hearts. 5 To determine whether agrin affects ...

A blood clot in the veins that drain the blood from the brain is called a sinus or cerebral vein thrombosis. It is an uncommon type of clot, affecting about 1500 people in the United States per year.

Figure. Pressure-volume loops of the left ventricle (LV) before and after transcatheter tricuspid valve repair (TTVR). *Values were acquired before the TTVR procedure within routine right heart ...

Cardiac magnetic resonance imaging can identify rare causes of recurrent stroke, such as congenital ventricular diverticulum. Congenital ventricular diverticulum is a protrusion of all 3 cardiac ...