Boosting a natural molecule that fuels cellular repair helps brain cells stay organized - a change that may slow memory loss.

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Poly(ADP-ribose) polymerase 1 (PARP1) is one ...

A new gene-editing technique enables the correction of multiple genetic mutations simultaneously, transforming the prospects ...

Our free DNA Reverse Complement tool is an indispensable utility for researchers, students, and technicians in molecular biology and genomics. Whether you’re designing PCR primers, verifying ...

Targeted DNA editing by CRISPR technology has great potential for applications in biotechnology and gene therapy. However, precise gene editing remains a challenge largely due to insufficient control ...

The human genome consists of 3 billion base pairs, and when a cell divides, it takes about seven hours to complete making a copy of its DNA. That's almost 120,000 base pairs per second. At that ...

Bacteria encode a variety of reverse transcriptases (RTs) that evolved from mobile group II intron RTs to perform different cellular functions. A previous study found that one such domesticated group ...

For decades, the dream of fixing harmful mutations in mitochondrial DNA felt out of reach. Scientists have long known these mutations cause serious diseases that pass down only through mothers. They ...

The research, published today as a Reviewed Preprint in eLife, is described by the editors as a landmark study with compelling evidence on how an important player in DNA repair – the RAD51 filament – ...

Researchers have uncovered answers that provide the detail to explain two specific DNA repair processes that have long been in question. Researchers from the University of Birmingham have uncovered ...