Inflammation is an important driver of atherosclerosis, the underlying pathology of cardiovascular diseases. Therefore, therapeutic targeting of inflammatory pathways is suggested to improve ...

† School of Chemical and Biological Engineering, Seoul National University, Seoul 151-744, Republic of Korea ‡ Severance Integrative Research Institute for Cerebral & Cardiovascular Diseases, Yonsei ...

The intracellular sensing protein termed NLRP3 (for NACHT, LRR, and PYD domains-containing protein 3) forms a macromolecular structure called the NLRP3 inflammasome. The NLRP3 inflammasome plays a ...

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