The San Francisco 49ers had three defensive linemen go down with injuries in their Week 3 win over the Arizona Cardinals according to head coach Kyle Shanahan who spoke with reporters Monday on a ...

The San Francisco 49ers on Wednesday had six players out of practice because of injury and another six players limited by injury leading up to their Week 4 matchup with the Jacksonville Jaguars. While ...

The San Francisco 49ers are locking up one of their top young defenders on a long-term contract. According to Fox Sports's Jordan Schultz, the 49ers and cornerback Deommodore Lenoir have agreed to a ...

The San Francisco 49ers may be without one of their starting safeties to begin the regular season. According to ESPN’s Nick Wagoner, safety Malik Mustapha sustained an ACL injury in the 49ers’ ...

Brock Purdy's toe injury isn't the only injury obstacle facing the San Francisco 49ers quarterback group. According to NFL Media's Ian Rapoport, quarterback Mac Jones after Sunday's game said he ...

The San Francisco 49ers had to hold on for dear life, but they escaped New Orleans with a 26-21 win and a 2-0 record to begin the 2025 season. San Francisco took an early lead and while the Saints ...

The San Francisco 49ers on Monday opened the practice window for second-year safety Malik Mustapha. Mustapha was participating in the individual portion of Monday's bonus practice for the 49ers ...

The San Francisco 49ers will face one of the best defenses in the NFL without two key starters according to their official Week 8 injury report. Quarterback Brock Purdy and wide receiver Ricky ...

The San Francisco 49ers didn't have any positive updates for their injured offensive players after Thursday's practice, but a pair of starters on defense were upgraded participants from Wednesday's ...