Publisher Nicalis and developer Edmund McMillen announced The Binding of Isaac: Repentance+ will launch for the Nintendo Switch 2 in Q1 2026. A physical edition will be available for $69.99 on the ...

Take full control with The Binding of Isaac Mod Menu—spawn any item, adjust stats, edit floors, and toggle perks instantly. Create your ultimate custom run now. Transform your Isaac experience into a ...

Orlando Magic big man Jonathan Isaac is releasing his new signature sneaker, the Judah 2, which will feature six Bible verses. For Isaac, an outspoken Christian with many conservative views, the goal ...

For some cultures, the practice of cranial deformation may have offered individuals a path to privilege later in their lives. The elongated skull of a person who lived in the Colca Valley of highland ...

Roguelike Games After 13 long years, The Binding Of Isaac creator's new tactical RPG Mewgenics finally gets a proper gameplay reveal showing off all the horrifying atrocities your kitties will be a ...

Abstract: The classification of DNA-binding proteins (DBPs) and RNA-binding proteins (RBPs) is essential for understanding molecular interactions and regulatory functions. However, the existing ...

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The Last of Us Season 2 Episode 4 just introduced Isaac, the commander of the Washington Liberation Front – and the show has an opportunity to improve the game in one way. Don’t be fooled, though: he ...

A hit PS5 game bundle released on the PS Store back in November 2021, but it’s never once been on sale in any promotions. Players have pointed out that The Binding of Isaac: Repentance — an ultimate ...

Daniel has been playing games for entirely too many years, with his Steam library currently numbering nearly 750 games and counting. When he's not working or watching anime, he's either playing or ...