染色体末端受到称为端粒的特殊结构的保护,端粒对于维持染色体稳定性和限制细胞生长至关重要。端粒上存在一种名为POT1的蛋白质,它在调节这些保护性末端的长度方面发挥着独特的作用。本文系统地测试了POT1的多种突变,以了解这些变化如何影响端粒的维持。
To be eligible for funding, applicants must meet CIRM’s requirements, which align with CIRM’s mission and funding opportunity objectives. Detailed information on common eligibility requirements and ...
Chloe B Fishman, Kate D Crawford, Santi Bhattarai-Kline, Darshini Poola, Karen Zhang, Alejandro Gonzalez-Delgado, Matias Rojas-Montero, Seth L Shipman Bacteriophage genome editing can enhance the ...
The objective of this request for applications (RFA) is to solicit a highly qualified applicant to develop and manage the 2017 annual meeting in support of the CIRM SPARK program. The SPARK program ...
The adaptive immune system archives an evolving record of its antigen exposures throughout life, employing B and T cells whose receptors (BCRs and TCRs) undergo random gene rearrangements, and whose ...
Ayush D Midha, Yuyin Zhou, Bruno B Queliconi, Alec M Barrios, Augustinus G Haribowo, Brandon T L Chew, Cyril O Y Fong, Joseph E Blecha, Henry VanBrocklin, Youngho Seo, Isha H Jain Oxygen deprivation ...
Large language models (LLMs) can answer expert-level questions in medicine but are prone to hallucinations and arithmetic errors. Early evidence suggests LLMs cannot reliably perform clinical ...