This article explores how single-cell multiomics and spatial transcriptomics are illuminating early pregnancy, uncovering ...

Scientists at Brown University have developed CaBLAM, a bioluminescent tool that allows long-term, high-resolution imaging of living brain cells without external light.

The preprint is available here. DeepSpot2Cell predicts virtual single-cell spatial transcriptomics as follows: (1) During training, the model takes as input (i) the cropped cell tile defined by the ...

Spatial transcriptomics provides a unique perspective on the genes that cells express and where those cells are located. However, the rapid growth of the technology has come at the cost of ...

Single-cell RNA transcriptomics allows researchers to broadly profile the gene expression of individual cells in a particular tissue. This technique has allowed researchers to identify new subsets of ...

“Illumina’s…presentations and product descriptions revealed a workflow that infringed on the ‘607, ‘138, ‘505, and ‘487 patents, 10x Genomics and Prognosys Biosciences argued.” On October 21, 10x ...

ABSTRACT: Spatial transcriptomics is undergoing rapid advancements and iterations. It is a beneficial tool to significantly enhance our understanding of tissue organization and relationships between ...

Stem cells in most organisms typically take cues from adjacent cells. But new research from the Stowers Institute for Medical Research reveals planarian stem cells ignore their nearest neighbors and ...

Spatial transcriptomics is undergoing rapid advancements and iterations. It is a beneficial tool to significantly enhance our understanding of tissue organization and relationships between cells.

Biological systems are inherently three-dimensional—tissues form intricate layers, networks, and architectures where cells interact in ways that extend far beyond a flat plane. To capture the true ...

We introduce a novel deep learning framework, SpaGene, which integrates scRNA-seq data and spatial transcriptomics data through an encoder-decoder architecture with translators, and discriminators, ...

Abstract: Spatial transcriptomics has emerged as a transformative technology for mapping gene expression within tissue contexts, offering unprecedented insights into disease mechanisms. However, ...