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Nature Methods | 利用高效数据优化Low-N蛋白筛选方法
蛋白质工程(Protein Engineer)具有巨大的学术和工业潜力。然而,在浩瀚的蛋白质序列空间中进行搜索的能力限制了我们的设计,但是蛋白质功能序列空间却非常有限。在寻找功能序列时,工程师们必须警惕“你得到你筛选的”这一普遍存在的格言,这一格言告诫 ...
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