This article explores how single-cell multiomics and spatial transcriptomics are illuminating early pregnancy, uncovering ...

Background Chronic pancreatitis (CP) is a risk factor for pancreatic cancer, with inherited cases conferring a markedly increased risk. The underlying mechanisms driving malignant transformation by CP ...

TileDB today announced the launch of TileDB Carrara, the omnimodal data intelligence platform, as a Snowflake Connected App for Healthcare & Life Sciences. This integration enables organizations to ...

Scientists chart a comprehensive cell atlas of the developing human reproductive system, offering new clues into congenital disorders.

Neoantigen vaccines are at the forefront of cancer research, driving personalized immunotherapy and improving outcomes through targeted T-cell activation.

This repository provides a comprehensive and reproducible suite of R scripts for analyzing Spatial Transcriptomics (ST) data. It compares the performance and results of Seurat and Giotto, and ...

Hepatocellular carcinoma (HCC) remains one of the leading causes of cancer-related mortality worldwide, characterized by increasing incidence rates and challenging prognoses. This study integrates ...

Spatial transcriptomics is undergoing rapid advancements and iterations. It is a beneficial tool to significantly enhance our understanding of tissue organization and relationships between cells.

Biological systems are inherently three-dimensional—tissues form intricate layers, networks, and architectures where cells interact in ways that extend far beyond a flat plane. To capture the true ...

Abstract: Recent advances in high-throughput spatial transcriptomics (ST) technologies now enable high-throughput molecular profiling of cells while maintaining their spatial organization within ...

Formalin-fixed, paraffin-embedded (FFPE) tissues represent the predominant sample conservation method in clinical practice, yet degraded and crosslinked RNA has long limited whole-transcriptome ...