The 49ers have yet to open the practice window for Brandon Aiyuk to return, which should start to set in a harsh reality.

Ahead of the season, there wasn’t a firm timeline for Aiyuk, with head coach Kyle Shanahan throwing out Week 10 as a ...

What is the team's biggest offseason regret, and how will Kris Kocurek utilize his remaining defensive linemen?

Talk of Brandon Aiyuk returning to the San Francisco 49ers has been reduced to uncertainty over when, or if, he'll even be ...

The San Francisco 49ers will be getting some players back against the Los Angeles Rams, but their superstar WR remains out of ...

Brandon Aiyuk is not ready to return yet. Almost two weeks after Kyle Shanahan said the star wide receiver was close to ...

San Francisco 49ers general manager John Lynch joined Bay Area radio station KNBR on Thursday, sharing encouraging updates on ...

Game Time: 4:25 p.m. Aiyuk is currently not listed on this week's injury report. No other receiver is on the injury report ...

San Francisco 49ers wide receiver Brandon Aiyuk (knee) still hasn't played a single snap of football in 2025 after suffering ...

San Francisco head coach Kyle Shanahan said Wednesday that he's "pretty confident" Aiyuk (knee) will play at some point this season, David Lombardi of SFStandard.com reports.

The 49ers have stayed afloat despite numerous injuries thanks in large part to the play of backup quarterback Mac Jones.

San Francisco's been without its top wideout for the whole regular season. Here's what we know about his potential return.