Background Anti-C1q autoantibodies can disrupt normal complement function, contributing to the formation of pathogenic immune ...

Background Lupus nephritis (LN) is the most serious complication of SLE. Interstitial fibrosis is the dominant pathological ...

Background SLE is a chronic autoimmune disease with heterogeneous manifestations and variable outcomes. Geographic factors such as rural residence may influence disease severity, access to care and ...

Objective Peer mentoring has been shown to be an effective intervention for chronic conditions with evidence to suggest that ...

Background Social determinants of health (SDoH) contribute to inequities in rheumatic disease care and outcomes especially among individuals with rheumatoid arthritis (RA) and systemic lupus ...

Objective To investigate the effects of Qihuang Jianpi Zishen Granules (QJZG) on renal injury in SLE mice, focusing on macrophage M1/M2 polarisation mediated by the AMPK/ULK1 signalling pathway.

Objective To identify different clusters of SLE patients in remission based on patient-reported outcomes (PROs) and clinical factors that predict cluster membership. Methods A cross-sectional ...

The 2025 EULAR recommendations for the management of systemic lupus erythematosus (SLE) with kidney involvement followed the EULAR standardized operating procedures, by recruiting an international ...

Each year the Lupus Science & Medicine editorial team selects the most meritorious research papers to receive the Lupus Science & Medicine Paper of the Year Award. Primary considerations are the ...

Haematologic involvement in patients with systemic lupus erythematosus (SLE) is very common. The principal cytopenias in lupus result in anaemia, white cell deficits and thrombocytopenia. Anaemia may ...

Objective Despite widespread use of azathioprine (AZA) during pregnancy, no studies evaluated the impact of pregnancy on AZA metabolites 6-thioguanine nucleotide (6-TGN) and 6-methylmercaptopurine ...