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Hormonal Dysregulation, Hyperinsulinemia and Wellness Break the cycle that leads to chronic disease. Some eating patterns—especially consuming excessive amounts of processed carbohydrates—lead to chronically high levels of insulin. Insulin stimulates GLUT4 receptors on cells, allowing glucose to enter the cell. When these receptors are constantly stimulated, they down-regulate and become insulin resistant, forcing the pancreas to produce more insulin to stimulate the receptors. This pattern repe