SOLVED: Your job is to characterize the gene responsible for myotonic muscular dystrophy (MMD). A large family with many afflicted members has been identified as shown in the pedigree below. ASO analysis of an SNP which might be linked to the MMD locus detects two different alleles, morph 1 and morph 2. The results of the ASO analysis is shown below each individual in the pedigree. (Assume 1-1 genotype = MMD 1 / MMD+ 2) In the pedigree above, there are 30 individuals that can be scored for their
SOLVED: Your job is to characterize the gene responsible for myotoni…
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